Water treatment for the chemical and petrochemical industry is one of the most technically demanding areas of industrial wastewater management. Chemical manufacturing facilities generate complex wastewater streams containing solvents, acids, bases, heavy metals, surfactants, pharmaceutical intermediates, volatile organic compounds (VOCs), and recalcitrant organic contaminants. These wastewater streams often exhibit extremely high COD and BOD levels, significant pH fluctuations, and hazardous characteristics that require specialised treatment solutions. Effective effluent treatment plants (ETPs) for chemical industries typically include source segregation, equalisation, advanced oxidation processes (AOPs), biological treatment technologies such as SBR and MBBR, tertiary treatment, and Zero Liquid Discharge (ZLD) systems where mandated. Proper treatment helps facilities comply with CPCB and SPCB regulations, reduce environmental impact, protect groundwater resources, manage hazardous sludge responsibly, and support sustainable industrial growth. This guide explains the characteristics of chemical industry wastewater, key contaminants, ETP design considerations, treatment technologies, regulatory requirements, and best practices for chemical and petrochemical manufacturers in India.